Publications
- Ostrowska KM, Malkin A, Meade A, O'Leary J, Martin C, Spillane C, Byrne HJ, Lyng FM. Investigation of the influence of high-risk human papillomavirus on the biochemical composition of cervical cancer cells using vibrational spectroscopy. Analyst. 2010 Dec; 135(12):3087-93. (Project 8)
- Astbury K, McEvoy L, Brian H, Spillane C, Sheils O, Martin C, O'Leary JJ. MYBL2 (B-MYB) in Cervical Cancer: Putative Biomarker. Int J Gynecol Cancer. 2011 Feb;21(2):206-12. (Project 8)
- Baier T, Hansen-Hagge TE, Gransee R, Crombé A, Schmahl S, Paulus C, Drese KS, Keegan H, Martin C, O'Leary JJ, Furuberg L, Solli L, Grønn P, Falang IM, Karlgård A, Gulliksen A, Karlsen F. Hands-free sample preparation platform for nucleic acid analysis.Lab Chip. 2009 Dec 7;9(23):3399-405. Epub 2009 Sep 30. PMID: 19904407
- Kelly JG, Cheung KT, Martin C, O'Leary JJ, Prendiville W, Martin-Hirsch PL, Martin FL. A spectral phenotype of oncogenic human papillomavirus-infected exfoliative cervical cytology distinguishes women based on age. Clin Chim Acta. 2010 Mar 30. PubMed PMID: 20359472.
- Keegan H, Mc Inerney J, Pilkington L, Gronn P, Silva I, Karlsen F, Bolger N, Logan C, Furuberg L, O'Leary J, Martin C. Comparison of HPV detection technologies: Hybrid capture 2, PreTect? HPV-Proofer and analysis of HPV DNA viral load in HPV16, HPV18 and HPV33 E6/E7 mRNA positive specimens. J Virol Methods, 155, 61-6. (2009) (Project 8)
- Bolger N, Heffron C, Regan I, Sweeney M, Kinsella S, McKeown M, Creighton G, Russell J, O'Leary J. Implementation and evaluation of a new automated interactive image analysis system. Acta Cytol. 2006 Sept-Oct; 50(5):481-2. PMID: 17017432
- Martin CM, Spillane C, Kehoe L, O'Leary JJ. Gene Discovery in Cervical Cancer: towards diagnostic and therapeutic biomarkers. Mol Diagn and Ther, 2007; 11(5):277-90. PMID: 17963416.
- Martin CM, Astbury K, O'Leary JJ. Molecular Profiling of Cervical Neoplasia. Expert Reviews in Molecular Diagnostics, 2006; 6(2), 217-229.
- Astbury K, Martin CM, Ring M, Pilkington L, Bolger N, Sheils O, O'Leary JJ. Future Molecular Aspects of Cervical Cytology. Current Diagnostic Pathology, 2006; 12, 104-113.
- Martin CM, Astbury, K, O'Leary JJ. Identification of Cell Cycle Regulatory Molecules as Biomarkers in Cervical Cancer by Gene Expression Profiling, and Validation by Immunohistochemistry and RT PCR. Methods in Molecular Medicine. Edited by Humana Press. In press.
- Martin CM. O'Leary JJ. Cerviva The Irish Cervical screening research consortium. DMMC Newletter. August 2007. (pdf download)
- Martin CM, O'Leary JJ. Working towards a world class cervical screening program for Irish women. Cancerwise, 2007, 6(2) 17-21. (pdf download)
- O'Leary JJ. Working towards a world class cervical screening program for Irish women. Cancer Professional, 2007
- Astbury K, Martin CM, Ring M, O'Leary JJ. Molecular Markers in Human Papilloma Virus-induced Female Genital Tract Cancers. Disease Markers. In press.
Presentations
Posters (P) and Oral Presentations (O)
- Keegan H, Pilkington L, Jamison J, Wilson R, Carson J, Martin CM, O’Leary JJ. Comparison of HPV DNA detetion technologies: Hybrid capture II (Qiagen), Cervista™ HPV HR (Hologic UK Ltd) in a Northern Irish Screening Population. Mod Pathol 2010; 23(S1): 85A-109A. (Project 8)
- Keegan H, Pilkington L, Jamison J, Wilson R, Carson J, Martin CM, O’Leary JJ. Comparison of HPV DNA detetion technologies: Hybrid capture II (Qiagen), Cervista™ HPV HR (Hologic UK Ltd) in a Northern Irish Screening Population. Laboratory Investigation 2010; 90: 85A–109A. (Project 8)
- Jeney C, Mózes J, Varga N, Benczik M, Kovács A, Kaltenecker B, Szenthe B, Takács T, Kurucz M, Lukács A, Keegan H, Pilkington L, Spillane CD, Martin CM, J. O'Leary JJ. A novel expression biomarker set has high accuracy to predict CIN1+ lesions using routine cervical cytology specimens. International Papillomavirus Conference Montreal, July 2010 (P) (Project 8)
- Mc Inerney J, H Keegan, L Pilkington, A Loy, C White, S Delamere, F Karlsen O Sheils, CM Martin, F Mulcahy and JJ O' Leary. HPV prevalence and persistence in a cohort of HIV positive women in Ireland. International Papillomavirus Conference Montreal, July 2010 (P) (Project 6)
- White C, Ruttle C, Pilkington L, McInerney J, Keegan H, O’ Donnell A, Stapleton M, .Flannelly G, O’Leary JJ, Martin CM. Significance of HPV mRNA testing and cigarette smoking in risk assessment for high grade cervical disease. European Federation for Colposcopy and Cervical Pathology Meeting 2010. Berlin 27-29th May. (P) (Project 5)
- Kehoe L, Spillane CD, Gallagher M, Sheils O, Martin C, O’Leary JJ. Investigation of the p16[INK4A] Pathway. United States and Canadian Academy of Pathology (USCAP) Annual Meeting 2010 (P) (Project 8)
- Kehoe L, Spillane CD, Gallagher M, Sheils O, Martin C, O'Leary JJ. miRNA Profiling in Cervical Cancer. United States and Canadian Academy of Pathology (USCAP) Annual Meeting 2010 (P) (Project 8)
- Kehoe L, Spillane CD, Gallagher M, Martin CM, O’Leary JJ. The p16INK4A Pathway in Cervical Cancer. International Papillomavirus (IPV) Meeting 2009 (P) (Project 8)
- Spillane CD, Kehoe L, Keegan H, Sheils O, Martin CM, O’Leary JJ. Silencing of HPV Viral Oncogenes E6 and E7 in Cervical Cancer. 5th Annual Cancer Conference 2008 (P) (Project 8)
- Spillane CD, Kehoe L, Keegan H, Sheils O, Martin CM, O’Leary JJ. Silencing of HPV Viral Oncogenes E6 and E7 in Cervical Cancer. Irish Association of Cancer Research (IACR) Annual Meeting 2008 (P) (Project 8)
- White C, Ruttle C, Pilkington L, Flannelly G, O'Leary JJ, Martin CM. Significance of HPV mRNA testing and cigarette smoking in risk assessment for high grade cervical disease. International Papillomavirus Meeting, July 3-8, 2010. (P) (Project 5)
- Spillane CD, White C, Linder K, McEligott T, Kehoe L, Sheils O, Martin CM, O'Leary JJ. The NSAID Sulindac inhibits proliferation and induces apoptosis in cervical cancer cell lines. International Papillomavirus Meeting 2010. (Montréal, Canada) July 3-8, 2010. (P) (Project 8)
- Murphy JC, Sharp L, Carsin A-E, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). HPV infection and vaccination: levels of knowledge and attitudes among primary care physicians. EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) (Project 3)
- Keegan H, Baier T, Hansen-Hagge T, Karlsen F, Gullicksen A, Gronn P, Solli L, Mielnik M, Furuberg L, Koltay P, Riegger L, Bolger N, O'Leary JJ, Martin CM. Lab on a chip: the future of cervical pre-cancer diagnostics. USCAP 2010 (O) (Project 8)
- O'Leary, JJ Keegan H, Pilkington L, Jamison J, Wilson R, Carson J, Martin CM, Comparison of HPV DNA detection technologies: Hybrid capture II (Qiagen), Cervista™ HPV HR (Hologic UK Ltd) in a Northern Irish Screening Population. 17th International Congress of Cytology, Edinburgh, Scotland, 16th-20th May 2010. (O). (Project 5)
- C.White, C. Ruttle, L. Pilkington, G.Flannelly, J.J. O'Leary, C.M Martin. Significance of HPV mRNA testing and cigarette smoking in risk assessment for high grade cervical disease. 5th European Congress of the European Federation for Colposcopy and Cervical Pathology 27 - 29 May 2010. (P) (Project 5)
- Murphy JC, Sharp L, Carsin A-E, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). HPV infection and vaccination: Levels of knowledge and attitudes among primary care physicians. EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) (Project 3)
- Mc Inerney J, Keegan H, Pilkington, L, Sheils O, Martin C.M., Loy A, Delamere S, Barrett M, Griffin M, Lyons F, Mulcahy F, O'Leary JJ. Human papillomavirus DNA and mRNA prevalence and persistence in human immunodeficency virus positive women. EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) (Project 6)
- Keegan H, Pilkington L, Jamieson J, Wilson RT, Carson J, Martin CM, O'Leary JJ. Comparison of HPV DNA detection technologies; Hybrid Capture 2 (Qiagen), Cervista™ (Hologic UK Ltd) in a Northern Irish screening population EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) and USCAP 2010. (Project 5)
- Keegan H, Pilkington L, Mc Inerney J, Pal-Szenthe B, Benczik M, Kaltenecker B, Mózes J, Kovács A, Solt A, Bolger N, Jeney C, O'Leary JJ, Martin CM. Comparison of HPV detection technologies; Hybrid Capture 2 (Qiagen), full-spectrum HPV (Genoid), Genoid Molecular Beacon Real-Time HPV assay with genotyping by Linear Array (Roche) and Genoid HPV Elisa Genotyping Assay in an Irish colposcopy population. EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) (Project 8)
- Loy A, McInerney J, Delamere S, Keegan H, Pilkington L, Sheils O, Lyons F, Martin C, J O' Leary JJ, and Mulcahy F. "Prevalence and persistence of integrated oncogenic HPV in HIV positive women. CROI February 2010 - 17th Conference on Retrovirus & Opportunistic infection. (P) (Project 6)
- Spillane CD,Kehoe L, Sheils O, Martin CM, O'Leary JJ. Transcriptome analysis of oncogene silenced HPV 16 positive carcinoma cells. EUROGIN February 2010 - Cervical Cancer Preventions: 20 years of progress & a path to the future. (O) (Project 8)
- CD Spillane, L Kehoe, O Sheils, CM Martin and JJ O'Leary. NSAID, sulindac, inhibits proliferation and induces apoptosis in cervical cancer cells. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- CD Spillane, L Kehoe, O Sheils, CM Martin, JJ O'Leary. Silencing of HPV Viral Oncogenes E6 and E7 in Cervical Cancer. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- KM Ostrowska, A Malkin, HJ Byrne, C Martin, JJ O'Leary, FM Lyng. Raman Spectroscopy: A Novel Tool for Cervical Cancer Screening. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- J Mc Inerney, H Keegan, L Pilkington, O Sheils, CM Martin, A Loy, S Delamere, M Barrett, M Griffin, F Lyons, F Mulcahy, JJ O'Leary. Human Papillomavirus DNA and mRNA Prevalence and Persistence in a Cohort of Human Immunodeficency Virus Positive Women in Ireland. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 5)
- L Kehoe, CD Spillane, M Gallagher, O Sheils, C Martin, JJ O'Leary. miRNA Profiling in Cervical Cancer. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- H Keegan, T Baier, T Hansen-Hagge, F Karlsen, A Gullicksen, P Gronn, L Solli, M Mielnik, L Furuberg, P Koltay, L Riegger, N Bolger, JJ O'Leary, CM Martin. Lab-on-a-Chip: The Future of Cervical Pre-Cancer Diagnostics. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- L Kehoe, CD Spillane, M Gallagher, O Sheils, C Martin, JJ O'Leary. Investigation of the p16[INK4A] Pathway. Modern Pathology, February 2010, 23 Supplement 1S, Supp: 4A-466A. (Project 8)
- CD Spillane, L Kehoe, O Sheils, CM Martin, JJ O'Leary. Silencing of HPV Viral Oncogenes E6 and E7 in Cervical Cancer. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 8)
- KM Ostrowska, A Malkin, HJ Byrne, C Martin, JJ O'Leary, FM Lyng. Raman Spectroscopy: A Novel Tool for Cervical Cancer Screening. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 8)
- J Mc Inerney, H Keegan, L Pilkington, O Sheils, CM Martin, A Loy, S Delamere, M Barrett, M Griffin, F Lyons, F Mulcahy, JJ O'Leary. Human Papillomavirus DNA and mRNA Prevalence and Persistence in a Cohort of Human Immunodeficency Virus Positive Women in Ireland. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 5)
- L Kehoe, CD Spillane, M Gallagher, O Sheils, C Martin, JJ O'Leary. miRNA Profiling in Cervical Cancer. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 8)
- H Keegan, T Baier, T Hansen-Hagge, F Karlsen, A Gullicksen, P Gronn, L Solli, M Mielnik, L Furuberg, P Koltay, L Riegger, N Bolger, JJ O'Leary, CM Martin. Lab-on-a-Chip: The Future of Cervical Pre-Cancer Diagnostics. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 8)
- L Kehoe, CD Spillane, M Gallagher, O Sheils, C Martin, JJ O'Leary. Investigation of the p16[INK4A] Pathway. Laboratory Investigation, February 2010, 90 Supplement 1S, Supp: 4A-466A. (Project 8)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Casey M, Sheils O, O'Leary JJ, Martin CM. Human papillomavirus prevalence and genotype distribution in Irish women attending routine cervical screening. 7th international Cancer Conference 2009. Institute of Molecular Medicine, Trinity College, Dublin, May 2009 (P) (Project 5)
- Mc Inerney J, Keegan H, Pilkington, L, C. Ni Cheallaigh, S. Delamere, M. Griffin, G. McHugh, P. Webster, M. Barrett, F. Lyons, C. Bergin, F. Mulcahy, S. Clarke, Sheils O, O'Leary JJ, Martin C.M. The prevalence and persistence of human papillomavirus in human immunodeficiency virus positive women. 7th international Cancer Conference 2009. Institute of Molecular Medicine, Trinity College, Dublin, May 2009 (P) (Project 6)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Casey M, Sheils O, O'Leary JJ, Martin CM. Human papillomavirus prevalence and genotype distribution in Irish women attending routine cervical screening. The British Society for Colposcopy & Cervical Pathology. Annual Scientific Meeting, University College, Dublin, May 2009 (P) (Project 5)
- Mc Inerney J, Keegan H, Pilkington, L, C. Ni Cheallaigh, S. Delamere, M. Griffin, G. McHugh, P. Webster, M. Barrett, F. Lyons, C. Bergin, F. Mulcahy, S. Clarke, Sheils O, O'Leary JJ, Martin C.M. The prevalence and persistence of human papillomavirus in human immunodeficiency virus positive women. The British Society for Colposcopy & Cervical Pathology. Annual Scientific Meeting, University College, Dublin, May 2009 (P) (Project 6)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Casey M, Sheils O, O'Leary JJ, Martin CM. Prevalence and Genotype Distribution of Human Papillomavirus in the Irish Cervical Screening Population. Friends of the Coombe Research Symposium, Coombe Women and Infants Hospital, December 2008 (O) (Project 5)
- Martin C.M. Mc Inerney J, Keegan H1, Pilkington, L1, C. Ni Cheallaigh, S. Delamere, M. Griffin, G. McHugh, P. Webster, M. Barrett, F. Lyons, C. Bergin, F. Mulcahy, S. Clarke, Sheils O, O'Leary JJ. Human papillomavirus prevalence and persistence, in the cervix of women with human immunodeficiency virus. Friends of the Coombe Research Symposium, Coombe Women and Infants Hospital, December 2008 (O) (Project 6)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Casey M, Sheils O, O'Leary JJ, Martin CM. Prevalence and genotype distribution of Human Papillomavirus in the Irish cervical screening population. EUROGIN November 2008 - Joining forces for cervical cancer prevention. (O) (Project 5)
- Martin CM, Mc Inerney J, Keegan H, Pilkington L, Ni Cheallaigh C, Delamere S, Griffin M, McHugh G, Webster P, Barrett M, Lyons F, Bergin C, Mulcahy F, Clarke S, Sheils O, O'Leary JJ. Human papillomavirus prevalence and persistence, in the cervix of women with human immunodeficiency virus. EUROGIN November 2008 - Joining forces for cervical cancer prevention. (O) (Project 6)
- Keegan H, Mc Inerney J, Pilkington L, Gronn P, Silva I, Karlsen F, Bolger N, O'Leary JJ, Martin CM. Evaluation of HPV DNA and mRNA detection technologies for detecting HPV in cervical cytology specimens. Pathological Society for Great Britain and Ireland, Winter Meeting, January 2008. (O) (Project 8)
- Keegan H, Mc Inerney J, Pilkington L, Gronn P, Silva I, Karlsen F, Bolger N, Logan C, Furuberg L, O'Leary JJ, Martin CM. Comparison of PreTect? HPV-Proofer and Hybrid Capture 2 for HPV detection with viral load analysis of HPV16, HPV18 and HPV33 E6/E7mRNA positive specimens. British Society for Clinical Cytology, Dublin, September 2008. (O) (Project 8)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Sheils O, O'Leary JJ, Martin C. Human papillomavirus prevalence and genotype distribution in the Irish cervical screening population. British Society for Clinical Cytology Annual Meeting, Dublin, September 2008. (O) (Project 5)
- Murphy J, Sharp L, Martin C, Sheils O, Pilkington L, O'Leary J. Irish women's views on cervical screening, HPV infection and HPV vaccination. Findings from a qualitative focus group study. British Society for Clinical Cytology, Dublin, September 2009. (O) (Project 3)
- Keegan H, Baier T, Hansen-Hagge T, Karlsen F, Gullicksen A, Gronn P, Solli L, Mielnik M, Furuberg L, Koltay P, Riegger L, Bolger N, O'Leary JJ, Martin CM. Lab on a chip: The future of cervical pre-cancer diagnostics. International Cancer Conference, Trinity College Dublin, May 2009. (P) (Project 8)
- Singh S, Martin CM, Pilkington L, O'Toole S, Keegan H, Cleary S, Prendiville W, Darcy T. M.J. Turner MJ, O'Leary JJ. Predicting disease recurrence using HPV testing post colposcopic treatment for cervical intraepithelial neoplasia. CERVIVA; An interim report. British Society for Colposcopy and Cervical Pathology Annual Scientific Conference, University College Dublin, May 2009. (P) (Project 5)
- Keegan H, Baier T, Hansen-Hagge T, Karlsen F, Gullicksen A, Gronn P, Solli L, Mielnik M, Furuberg L, Koltay P, Riegger L, Bolger N, O'Leary JJ, Martin CM. Lab on a chip: The future of cervical pre-cancer diagnostics. British Society for Colposcopy and Cervical Pathology Annual Scientific Conference, University College Dublin, May 2009. (P, O in absentia) (Project 8)
- Jeney C, Sebe A, Szenthe B, Kovacs A, Kaltenecker B, Benczik M, Keegan H, Martin C, O'Leary J, Takacs T. High throughput HPV screening using a one step multiplex real-time PCR based system. 25th International Papillomavirus Conference, Malmo, Sweden, May 2009. (P, A) (Project 8)
- Solli L, Gullicksen A, Baier T, Gransee R, Hansen-Hagge T, Mielnik M, Johansen I-R, Furuberg L, Rigger L, Koltay P, Martin C, Keegan H, O'Leary J, Karlsen F et al. Development of automatic chip-based detection of mRNA. Discovery to Diagnostics Conference, San Diego, California, October 2008. (P) (Project 8)
- O'Leary JJ. p16 an important marker of cervical dyskaryosis. BSCC meeting September 2008. (O) (Project 8)
- O'Leary JJ. Biomarkers in cervical cancer. BSCCP meeting May 2009 (O) [Project 1,8]
- O'Leary JJ. Molecular Pathology -impact on future diagnosis. Biomedical Science Congress, Sept 2009, Birmingham, UK (O) [Project 1,5,8]
- O'Leary JJ. Functional inactivation of HPV transforming genes: new insights into cervical cancer. Guinness Meeting Dublin 2009 (O) [Project 5, 8]
- O'Leary JJ. Cancer, Genes, Proteins and Stemness. Professorial Inaugural Lecture as Chair of Pathology at TCD, 17th May, 2007.
- Keegan H, Mc Inerney J, Pilkington L, Grønn P, Silva I, Karlsen F, Bolger N, O'Leary JJ, Martin CM. Evaluation of HPV DNA and mRNA Detection Technologies for Detecting HPV in Cervical Cytology Specimens. Oral presentation at Pathological Society of Great Britain and Ireland, Winter Meeting, Oxford 7-9th January 2008. (Project 8)
- Keegan H, Mc Inerney J, Pilkington L, Grønn P, Silva I, Karlsen F, Bolger N, O'Leary JJ, Martin CM. Comparison of HPV Detection technologies; Hybrid Capture II (Digene), Pretect HPV Proofer (Norchip) and Real time PCR for Detection of HPV in cervical cytology specimens. Oral Presentation at Eurogin, New Strategies in Cervical Cancer Prevention, Monte Carlo, Monaco, 4-6th Oct, 2007. (Project 8)
- Martin, CM. HPV DNA and mRNA testing in the Irish Cervical Screening Population. Presentation at Norchip Satellite Symposium meeting, Eurogin, New Strategies in Cervical Cancer Prevention, Monte Carlo, Monaco, 4-6th Oct, 2007. (Project 5)
- O'Shea D Doolan C, Bolger N, Cullen R, Pilkington L, Martin C, Magee D, Griffin M, Gibbons D, O'Leary JJ. Development of a virtual web based external quality assessment (EQA) scheme in Cytopathology. Modern Pathology May 2008; 21 [Supplement 2s]: S1-S55. (Project 2)
- O'Shea D Doolan C, Bolger N, Cullen R, Pilkington L, Martin C, Magee D, Griffin M, Gibbons D, O'Leary JJ. Development of a virtual web based external quality assessment (EQA) scheme in Cytopathology. Laboratory Investigation, Jan 2008; 88 [Supplement 1f]: 4a - 396a. (Project 2)
- Ni Cheallaigh C, Sheils O, Griffiths S, Webster P, Martin C, McInerney J, Keegan H, O'Leary J, Lyons F, Bergin C, Mulcahy F, Clarke S. Oncogenic HPV sustypes in HIV-positive women. The 18th European Congress of Clinical Microbiology and Infectious Diseases (Barcelona, 19th -22nd April 2008) (Project 6)
- Murphy J, Sharp L, Carsin AE. Attitudes of GPs towards HPV vaccination: results from a national survey in Ireland. UK National Cancer Research Institute Cancer Conference, Birmingham, 2nd October 2007. (Project 3)
- Murphy J, Sharp L, Carsin AE. GPs' views on screening for cervical cancer and HPV testing: results from a national survey in Ireland. United Kingdom Association of Cancer Registries Annual Conference 2007, Birmingham, 31st October 2007. (Project 3)
- Kehoe L, Ring M, Pilkington L, Keegan H, Astbury K, Sheils O, Griffin M, Gaffney E, Gibbons D, Martin CM, O'Leary JJ. Villoglandular Adenocarcinoma of the cervix: High Risk HPV infection is associated with disruption of DNA licensing and replisome proteins. Poster at Pathological Society of Great Britain and Ireland, Winter Meeting, Oxford 7-9th January 2008. (Project 8)
- Keegan H, Mc Inerney J, Pilkington L, Grønn P, Silva I, Karlsen F, Bolger N, O'Leary JJ, Martin CM. Evaluation of HPV DNA and mRNA Detection Technologies for Detecting HPV in Cervical Cytology Specimens. Poster presentation at 24th International Papillomavirus Conference and Clinical Workshop in Beijing, China, from November 3rd-9th 2007. (Project 8)
- Martin C, Astbury K, Becker C, Henfrey R, Sherlock J, Guenther S, Sheils O, O'Leary JJ. MicroRNA signatures in Cervical Cancer: suggests hierarchical miRNA control of gene expression. Laboratory Investigation, 2007 (87) Supplement 1, 207A. (Project 8)
- O'Toole SA, Laios A, Sheppard B, Gleeson N, D'Arcy T, McGuinness E, Ring M, Gaffney E, Flavin R, Martin C, O'Brien J, O'Connell D, Sheils O, Cahill D, O'Leary JJ. miRNA Signatures in Primary versus Recurrent Ovarian Cancers. Laboratory Investigation, 2007 (87) Supplement 1, 209A. (Project 8)
- Ring M, Crowther S, Martin C, Astbury K, Sheils O, Griffin M, Gaffney E, Gibbons D, O'Leary JJ. Significant dysregulation of DNA replication license and replisome proteins in villoglandular carcinomas of the cervix indicates possible aggressive biological behaviour. Laboratory Investigation, 2007 (87) Supplement 1, 970A. (Project 8)
- Martin CM, Astbury K, Henfrey R, Sheils O, Gallagher M, Heffron C, Logan C, O'Leary JJ. miRNA Expression Signatures in Cervical Cancer. Modern Pathology; 2006 (19): Supplement 1, 171A. (Project 8)
- Astbury K, Martin CM, Smyth P, O'Leary JJ. Identification of Cell Cycle Regulatory Molecules as Biomarkers in Cervical Cancer using Gene Expression Profiling. Modern Pathology; 2006 (19): Supplement 1, 171A. (Project 8)
- Martin CM, Astbury K, Henfrey R, Sheils O, Gallagher M, Heffron C, Logan C, O'Leary JJ. miRNA Expression Signatures in Cervical Cancer. Laboratory Investigations, 2006 (86): 189A. (Project 8)
- Astbury K, Martin CM, Smyth P, O'Leary JJ. Identification of Cell Cycle Regulatory Molecules as Biomarkers in Cervical Cancer using Gene Expression Profiling. Laboratory Investigations, 2006 (86): 171A. (Project 8)
- Murphy J, Sharp L, Martin C, Pilkington L, Sheils O, O'Leary J, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). Women's knowledge and attitudes regarding cervical screening and human papillomavirus (HPV): Focus group findings from Ireland. Oral presentation at British Society for Clinical Cytology, 47th Annual Scientific Meeting, Dublin, Sept 2008. (Project 3)
- Murphy J, Sharp L, Carsin AE HPV infection, testing and vaccination: knowledge, attitudes and practices among GPs. Poster presentation at British Society for Colposcopy and Cervical Pathology conference 2008. (Birmingham10/11 April 2008) (Project 3)
- Murphy J, Sharp L, Carsin AE GPs' knowledge of HPV infection and vaccination: Is there a need for further professional education. Poster presentation at NHS confederation conference, Delivering better health services. (Manchester 4/5 June 2008). (Project 3)
- Murphy J, Sharp L, Martin C, Pilkington L, Sheils O, O'Leary J, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA) Irish women's attitudes & knowledge of cervical screening & human papillomavirus (HPV): Preliminary findings from a focus group study. Poster presentation at UCC/Cork University Teaching Hospitals Health Research Day, 6 June 2008. (Project 3)
- Spillane CD, Kehoe L, Sheils O, Martin CM, O'Leary JJ. Silencing of HPV viral oncogenes E6 and E7 in cervical cancer. EUROGIN 2008 JOINING FORCES FOR CERVICAL CANCER PREVENTION NICE, France, November 12-15, 2008. (Project 8)
- Mc Inerney J, Pilkington L, Keegan H, Ring M, Bolger N, Casey M, Sheils O, O'Leary JJ, Martin CM. Prevalence and genotype distribution of Human Papilloma Virus in the Irish Cervical Screening Population. EUROGIN 2008 JOINING FORCES FOR CERVICAL CANCER PREVENTION NICE, France, November 12-15, 2008. (Project 5)
- Kehoe L, Spillane CD, Martin C, O'Leary JJ. Elucidation of the role of the p16INK4A pathway in the cell cycle and its relationship with the Human Papilloma Virus in cervical cancer. EUROGIN 2008 JOINING FORCES FOR CERVICAL CANCER PREVENTION NICE, France, November 12-15, 2008. (Project 8)
- Martin CM, Mc Inerney J, Keegan H, Pilkington, L, Ni Cheallaigh C, Delamere S, Griffin M, McHugh G, Webster P, Barrett M, Lyons F, Bergin C, Mulcahy F, Clarke S, Sheils O, O'Leary JJ. Human Papillomavirus prevalence and persistence, in the cervix of women with human immunodeficiency virus. EUROGIN 2008 JOINING FORCES FOR CERVICAL CANCER PREVENTION NICE, France, November 12-15, 2008. (Project 6)
- Normand C. A Comparison of the Thin Prep Imaging System and Manual Screening by Meta Analysis and Systematic Review. The British Society for Colposcopy and Cervical Pathology (BSCC) Annual Meeting, oral presentation, Dublin 2008. (Project 1)
- McInerney J, Pilkington L, Keegan H, Ring M, Bolger N, Sheils O, O'Leary J, Martin CM. Human Pappiloma Virus prevalence and genotype distribution in the Irish cervical screening population. The British Society for Colposcopy and Cervical Pathology (BSCC) Annual Meeting, oral presentation, Dublin 2008. (Project 5)
- Keegan H, McInerney J, Pilkington L, Grønn P, Silva I, Karlsen F, Bolger N, Logan C, Furuberg L and O'Leary JJ. Comparison of PRETECT HPV-proofer and hybrid capture II for HPV detection with viral load analysis of HPV 16, HPV 18 and HPV 33 E6/E7 mRNA positive specimens. The British Society for Colposcopy and Cervical Pathology (BSCC) Annual Meeting, oral presentation, Dublin 2008. (Project 8)
- O'Leary JJ. p16 and Replisome Associated Proteins in Cervical Pre-Cancer and Cancer. The British Society for Colposcopy and Cervical Pathology (BSCC) Annual Meeting, oral presentation, Dublin 2008. (Project 8)
- Hagmar B. Integration of Biomarkers in Cervical Cytology. The British Society for Colposcopy and Cervical Pathology (BSCC) Annual Meeting, oral presentation, Dublin 2008. (Project 8)
- Murphy J, Sharp L, Carsin AE Attitudes and knowledge of GPs towards HPV infection, testing and vaccination: results from a national survey in Ireland. Society of Social Medicine Conference, UK, oral presentation, Sept. 2008. (Project 3)
- Murphy J, Sharp L, Martin C, Pilkington L, Sheils O, O'Leary J, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). Attitudes and knowledge of GPs towards HPV infection, testing and vaccination: results from a national survey in Ireland. National Cancer Research Institute, Birmingham, oral presentation, Oct. 2008 (Project 3)
- Murphy J, Sharp L, Martin C, Pilkington L, Sheils O, O'Leary J, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). A focus group study in Ireland of women's views, attitudes and knowledge of cervical screening and Human Papillomavirus (HPV). National Cancer Research Institute, Birmingham, poster presentation, Oct. 2008 (Project 3)
- Murphy J, Sharp L, Martin C, Pilkington L, Sheils O, O'Leary J, on behalf of the Irish Cervical Screening Research Consortium (CERVIVA). What are women's views on cervical screening and HPV vaccination? A qualitative study in Ireland EUROGIN conference 2008: Joining forces for cervical cancer prevention. Nice, France, oral presentation, Nov. 2008. (Project 3)
- Baier T, Hansen-Hagge T, Gransee R, Crombé A, Solli L, Gulliksen A, Martin C, Keegan H, O'Leary JJ, Riegger L, Mielnik M, Furuberg L. Towards automatic chip-based detection of HPV mRNA in cervical samples. For presentation at Lab 09, Hannover, Germany. (Project 8)
- Baier T, Furuberg L, Hansen-Hagge T, Gransee R, Crombé A, Solli L, Gulliksen A, Martin C, Keegan H, Riegger L, Mielnik M, O'Leary JJ, Karlsen F. Towards point of care chip based diagnostics based on mRNA. For presentation at Lab 09, Hannover, Germany. (Project 8)
Abstracts Submitted
- Keegan H, Pilkington L, Mc Inerney J, Pal-Szenthe B, Benczik M, Kaltenecker B, Mózes J, Kovács A and Solt A, Bolger N, Jeney C, O’Leary JJ, Martin CM. Comparison of Hybrid Capture 2 (Qiagen), Full-Spectrum HPV (GenoID), GenoID Molecular Beacon real-time HPV Assay with genotyping by Linear Array (Roche) in an Irish colposcopy population. The British Society for Colposcopy and Cervical Pathology Annual Scientific Meeting, Liverpool March/ April 2011. (Project 8)
- Keegan H Pilkington L, Mc Inerney J, Pal-Szenthe B, Benczik M, Kaltenecker B, Mózes J, Kovács A and Solt A, Bolger N, Jeney C, O’Leary JJ, Martin CM. Comparison of HPV detection technologies; Hybrid Capture2 (Qiagen), Full-spectrum HPV (GenoID), GenoID Molecular Beacon Real-Time HPV Assay with genotyping by Linear array (Roche) and GenoID HPV ELISA genotyping assay in an Irish colposcopy population. United States and Canadian Association of Pathology Annual Meeting, San Antonio, Texas, February 2011 (P) (Project 8)
- Pilkington L, Keegan H, O’Toole S, Singh S, Cleary S, Prendiville W, Darcy T, Turner MJ,, Von Bunau G, Anglim M, O’Leary JJ, Martin CM. The utility of HPV testing in predicting disease recurrence post colposcopic treatment for cervical intraepithelial neoplasia. United States and Canadian Association of Pathology Annual Meeting, San Antonio, Texas, February 2011. (P) (Project 5)
- White C, Ruttle C², Pilkington L, McInerney J, Keegan H, O’Toole S, Spillane C, Sharp, L, O’Kelly R, Fitzpatrick M, Lenehan P, Flannelly G, O’Leary J, Martin CM. HPV DNA/mRNA testing and smoking as a risk factor in predicting high grade cervical disease in women predicting with low grade cervical lesions. Eurogin, Lisbon May 2011. (O) (Project 5)
- Pilkington L, Keegan H, O’Toole S, Singh S, Cleary S, Prendiville W, Darcy T, Turner MJ,, Von Bunau G, Anglim M, O’Leary JJ, Martin CM. HPV E6/E7 mRNA and HPV DNA testing in post colposcopic treatment surveillance of cervical intraepithelial neoplasia. Eurogin, Lisbon May 2011. (O) (Project 5)
- White C, Ruttle C, Pilkington L, McInerney J, Keegan H, O’Toole S, Spillane C, Sharp, L, O’Kelly R, Fitzpatrick M, Lenehan P, Flannelly G, O’Leary J, Martin CM. Utility of HPV DNA/mRNA testing and smoking as a risk factor in predicting high grade cervical disease in women predicting with abnormal smears. The British Society for Colposcopy and Cervical Pathology Annual Scientific Meeting, Liverpool March/ April 2011.(Project 5)
- White C, Ruttle C, Pilkington L, McInerney J, Keegan H, O’Toole S, Spillane C, Sharp, L, O’Kelly R, Fitzpatrick M, Lenehan P, Flannelly G, O’Leary J, Martin CM. HPV DNA/mRNA testing and smoking as a risk factor in predicting high grade cervical disease in women predicting with low grade cervical lesions. IACR meeting 2011. Feb (Project 5)
- Spillane CD, White C, Kehoe L, McEligot T, Sheils O, Martin CM and O'Leary JJ. The NSAID Sulindac inhibits proliferation and induces apoptosis in cervical cancer cell lines. United States and Canadian Association of Pathology Annual Meeting, San Antonio, Texas, February 2011 (P) (Project 8)
- Spillane CD, White C, Kehoe L, McEligot T, Sheils O, Martin CM and O'Leary JJ. Sulindac has anti-neoplastic activity towards cervical cancer cells. Eurogin, Lisbon May 2011. (O) (Project 8)
Papers Submitted
- Yusof A, Keegan H, Spillane CD, Sheils OM, Martin CM, O’Leary JJ, Zengerle R, Koltay P. “Inkjet- like” printing of single cells. Submitted to Nature Methods, February 2011. (Project 8)
- Martin CM, Spillane C, Keegan H, White C, O’Toole S, Sheils O, O’Leary JJ. Histology of Cervical Intraepithelial Neoplasia and the role of biomarkers. Submitted to Best Practice & Research Clinical Obstetrics & Gynecology, February 2011. (Project 8)
- Astbury, K, McEvoy, L, Gleeson, N, D'arcy, T, Spillane, C, Sheils, O, Martin, C, O'Leary, JJ Altered expression of kinetochore proteins nuf2 and hec 1 in cervical pre-cancer and cancer. Under review International J. of Surgical Pathology.
- Kehoe, L, Conlon, N, Ring, M, Keegan, H, Pilkington, L, Astbury, K, Geraghty, R, Crowther, S, Redmond, M, O Sheils, O, Gaffney, E, Gibbons, D, Martin, CM, O'Leary, JJ. Villoglandular Adenocarcinoma of the Cervix: High Risk HPV Infection is Associated with Disruption of DNA Licensing and Replisome Proteins. Submitted to Journal of Pathology.
